October 23, 2024
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Important points:
Standing for more than 10 hours each day increases your risk of orthostatic cardiovascular disease. Sitting may increase your risk of CVD, but standing may not.
Results from a cohort study published in the International Journal of Epidemiology showed that standing compared to sitting did not improve cardiovascular health.
Rather, standing may increase the risk of some cardiovascular problems, such as deep vein thrombosis, while sitting for long periods of time increases the risk of both CVD and orthostatic cardiovascular disease. may increase.
Data origin: Ahmadi M, et al. Int J Epidemiol. 2024;doi:10.1093/ije/dyae136.
“The key takeaway is that standing for long periods of time does not compensate for a sedentary lifestyle and can be dangerous for some people in terms of cardiovascular health,” says Sydney. said Dr. Matthew N. Ahmadi of the university’s School of Medicine and Health. said the lead study author, who lives in Australia, in a press release. “We found that spending more time on your feet does not improve long-term cardiovascular health and increases your risk of cardiovascular problems.”
According to Ahmadi et al., reducing sitting time and increasing standing time “may improve surrogate cardiovascular outcomes such as metabolic markers,” but research on the health outcomes this leads to is “Very few,” they write.
This study analyzed accelerometer data from 83,013 adults (mean age 61 years, 55.6% women) from UK Biobank, and analyzed the time spent sitting, standing, and standing still, as well as for significant CVD and We clarified the association with the risk of orthostatic cardiovascular disease.
Researchers defined major CVD as stroke, heart failure, and coronary heart disease, while orthostatic circulatory disease included orthostatic hypotension, varicose veins, and chronic venous insufficiency.
During 6.9 years of follow-up, this cohort experienced 6,829 cases of CVD and 2,042 cases of orthostatic cardiovascular disease.
Ahmadi et al. found that the risk of orthostatic cardiovascular disease increased by 22% for each additional hour of stationary time >12 hours per day (HR = 0.22, 95% CI, 0.16 to 0.29).
Each additional hour spent sitting for more than 10 hours per day was associated with a 26% increased risk of orthostatic cardiovascular disease (HR = 0.26; 95% CI, 0.18-0.36). Meanwhile, the results showed an association between standing for more than two hours a day and an 11% risk of orthostatic cardiovascular disease. Every additional 30 minutes increases the risk (HR = 0.11; 95% CI, 0.05-0.18).
On the other hand, when stationary time exceeded 12 hours per day, the risk of severe CVD increased by an average of 13% per hour (HR = 0.13; 95% CI, 0.1-0.16).
Sedentary time was associated with a 15% higher risk of severe cardiovascular disease for every hour spent >10 hours per day (HR = 0.15; 95% CI, 0.11-0.19).
Exposure time did not correspond to an increase in major CVD risks.
The researchers explained that there may be a “sitting-specific” mechanism behind the association with CVD.
“For example, lower cumulative energy expenditure while sitting and muscular and musculoskeletal activity while standing may partially explain the differences in the effects of the two postures.” the researchers wrote.
Ahmadi and colleagues acknowledged some limitations to the study, including the potential for misclassification of movement and posture.
After all, “for people who regularly sit for long periods of time, getting lots of incidental movement or structured exercise throughout the day may be a better way to reduce their risk of CVD.” ” said Dr. Emmanuel Stamatakis, a professor at the university. The University of Sydney and co-authors of the study said in a release. “Take regular breaks, walk around, go to walking meetings, take the stairs, take regular breaks when driving long distances, and use your lunch break to get away from your desk and get some physical activity. Let’s do it.”
References:
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